Dr. Abebaw B. Jemere

Dr. Abebaw B. Jemere |Clyto Access

National Institute for Nanotechnology, National Research Council Canada, Edmonton, Alberta

Keynote Speaker

Expertise:

Biography:

Dr. Abebaw Jemere obtained his PhD from the University of Alberta in 2003, specializing in bioanalytical chemistry and the applications of microfluidics devices for life science research. Currently, he is a Research Officer at National Research Council National Institute for Nanotechnology.  Prior to NINT he was staff scientist at CMC Microsystems (providing consultation and guidance in the areas of chemical and biological sensors, microfluidics, and microfabrication to universities and industry).  He also worked for a start-up company, Advanced Integrated Microsystems, developing a microfluidics based protein processing chip. Dr. Jemere‚Äôs research primarily focuses on developing miniaturized analytical techniques for the separation, detection and identification of biomolecules. He conducts research in the areas of capillary electrophoresis, capillary electrochromatography, immunoassay, metabolomics, proteomics, mass spectrometric detection and lab-on-a-chip technology as well as developing novel biosensors. Dr. Jemere has published over 24 manuscripts in peer reviewed journals and holds 2 patents. In collaboration with other NINT researchers, Drs. Brett and Harrison, he demonstrated an integrated matrix-free laser desorption ionization technique using nanostructured thin films for the separation, detection and identification of small molecules. In collaboration with Defence Research Development Canada, Dr. Jemere is developing biosensors via self-assembled nanostructures. This project will address fundamental problems with sensor systems using principles of good design so that the output technology is amenable to automated fluidic processing.

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Presentation:

Title: Nanostructured electrodes for ultrasensitive electrochemical impedance detection of pathogens

Abstract: Nanotechnology has tremendous potential to enhance the performance of biosensors. The chemical, electronic, and optical properties of nanomaterials generally depend on both their dimensions and their morphology. A major advantage of using nanomaterials in biosensing is the number of bioreceptor molecules immobilized on the detector surface can be as low as a single molecule. As a result the number of analyte molecules required to generate a measurable signal could be just a few providing very low limits of detection. As a sensitive, non-destructive, and label-free detection method, electrochemical impedance spectroscopy (EIS) has recently received considerable attention for the characterization of electrical properties in biological interfaces. We self-assembled gold nanoparticles on gold electrodes to yield multi-layered molecular structures for sensitive pathogen detection and in situ regeneration of the sensor electrode. The use of molecular self-assembly and gold nanoparticles plus EIS detection rendered a detection limit of 30 virus particles/ml for adenovirus 5 and 100 cells/ml for E-coli 0157:H7. The gold nanoparticle sensor surface could be self-assembled and regenerated at least 30 times without losing analytical performance. We also fabricated indium tin oxide nanoporous electrodes, using the glancing angle deposition (GLAD) technique, for disposable and yet highly sensitive EIS detection of pathogens. GLAD utilizes oblique angle physical vapor deposition combined with precision substrate rotation to engineer nano-columns. The combination of nanotechnology and EIS is an attractive and powerful concept for future chemical and biological sensors research and integration in to lab-on-a-chip devices for field deployable sensors.,

Related Conferences :

World Summit on Nanotechnology and Nanomedicine Research