Dr. Hassan A. Hemeg

Dr. Hassan A. Hemeg |Clyto Access

Taibah University. Saudi Arabia

Editorial Board Member

Expertise: Antimicrobial resistance

Biography: Dr. Hassan A. Hemeg completed Masters in Pathological Science from Sheffield University, UK and Ph.D. from King Abdulaziz University, Jeddah, Saudi Arabia. He has earned several honors such as Fellow of Institute of Biomedical Science, UK and Certified Canadian Accreditation Specialist for Health Care Facilities. He acquired training in Microbiology from Sheffield and Bristol Universities, U.K. and U.S. Department of Labor, Occupational Safety and Health Administration. He is a member, Secretary and Chairman of several Committees. He has published several papers in Journals of International repute.



Title: Nanomaterials: Applications in antibacterial therapy


Despite an array of potent antibiotics, bacterial infections, particularly those caused by nocosomial pathogens still remain a major cause of morbidity and mortality around the globe. These target the severely ill, hospitalized and immunocompromised patients who are vulnerable to infections. The option for treatment with antimicrobials is mostly empirical and not bereft of toxicity, teratogenicity and/or mutagenicity, hypersensitivity. The emergence of multi-drug resistant bacteria further aggravates the clinical problem as it has a direct impact on global public health because of the reduced potency of existing antibiotics. Moreover, there is a growing concern regarding biofilm-associated infections that are refractory to the currently available antimicrobial armory, leaving almost no treatment option. Thus, there is a pressing need to develop alternate bactericidal agents. 
The past decade has witnessed a substantial surge in the global use of nanomedicines as innovative tools for combating the high rates of antimicrobial resistance. Several metal and metal oxide nanoparticles have been reported for their antibacterial activity. The microbes are eradicated either by microbicidal effects of the nanoparticles such as release of free metal ions, cell membrane damage, DNA interaction, free radical generation, or by microbistatic effects followed by killing potentiated by the host's immune system. The effect of nanomaterials on the microbial biofilms along with the mechanisms by which the metallic nanoparticles annihilate multidrug-resistant bacteria will be discussed. Combinatorial therapeutic approach with the metallic nanoparticles may serve as adjunct to the existing antibiotics and may help to curb the mounting menace of bacterial resistance and nocosomial threat.

Related Conferences :

World Summit on Nanotechnology and Nanomedicine Research