Dr. Pradeep Mahajan

Dr. Pradeep  Mahajan |Clyto Access

Chairman & Managing Director, StemRx BioScience Solutions, India

Keynote Speaker

Expertise: Stem Cell Technology, Adult Stem Cells, Stem Cell Transplant

Biography: Dr. Pradeep Mahajan is a general surgeon with a lot of additional qualifications extending beyond his subject & adding additional experties over two decades. Dr P V Mahajan has got numerous national and international recognitions for his innovative work in field of medicine. As well as The government of India and Government of Maharashtra has honored him by appointing as consultant and panel doctor with the director general of Shipping and Labor department. He is also representing crucial position as certified surgeon for government of Maharashtra. Academically he has worked as associate Professor of surgery at Terna medical college, Navi Mumbai. He has been post graduate and under graduate teacher and examiner for the same. Socially he was president of rotary club and chair person for association of certified surgeons of Maharashtra. Dr P V Mahajan is graduate of SRTRMC medical college from Marathwada University with laurels of two gold medals, master in surgery MS from Marathwada university, Dip in Urology from Vienna university, member of American Medical Society as well many other academic and professional medical Institutes.Currently he is Chairman & Managing Director StemRx BioScience Solutions, India.,


Title: Regenerative Medicine and Cell Based Therapy: The Future of Organ Transplant?


Organ replacement is gradually becoming commonplace in modern medicine. Despite technological advances, shortage of donors and bioethical issues concerning transplantation has continually been a cause of concern. Additionally, immune-suppression in the individual is of paramount importance that determines success of the procedure. Regenerative medicine/Cell based therapy has shown tremendous potential in augmenting organ function as well as repair and regeneration of damaged organs. Furthermore, this promising field can be explored to address the current needs of organ transplantation namely inexhaustible source of tissues and immune-suppression free transplantation.Stem cells are capable of differentiation into diverse populations of specialized cell types. Along with the properties of self renewal and anti-inflammation, these cells are also potent immune-modulatory agents. In context of organ transplantation, the major advantage of mesenchymal stem cells (MSCs) is that they escape immune recognition and can inhibit immune responses. Additionally, MSCs have immune-regulatory effects on T-regulatory (CD4+/25high Foxp3 +) cells, B cells, NK cells and dendritic cells. MSCs exert species specific immune-modulation. Direct cell-cell contact and paracrine mechanisms have been described as the mechanisms by which mesenchymal stem cells (MSCs) exert their immune-modulatory role. The existing dogma of organ transplantation is being challenged by the advent of regenerative medicine. Mesenchymal stem cells present with unexplored properties in transplantation immunobiology and can contribute significantly towards evolution of newer therapeutic avenues in organ replacement.


Related Conferences :

Global Forum on Transplantation Research and Technologies